Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and links to their rpeorts go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	2322
interventional	1805
Observational	475
Registry	42

Studies over Time

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	979
Drug\|placebo	263
Biological	256
Behavioral	54
Other	53
Biological\|Drug	42
Biological\|Drug\|placebo	23
Device	18
Procedure	15
Biological\|placebo	13
Dietary Supplement	12
Drug\|Other	10
Diagnostic Test	8
Device\|Drug	7
Behavioral\|Other	6
Biological\|Other	5
Biological\|Procedure	4
Dietary Supplement\|placebo	4
Behavioral\|Biological	3
Behavioral\|Drug	3
Device\|Other	3
Dietary Supplement\|Drug	3
Other\|Procedure	3
Biological\|Drug\|Other	2
Drug\|Procedure	2
Genetic	2
Behavioral\|Diagnostic Test	1
Behavioral\|placebo	1
Biological\|Drug\|Procedure	1
Biological\|Other\|placebo	1
Diagnostic Test\|Drug	1
Dietary Supplement\|Drug\|Procedure	1
Dietary Supplement\|Other	1
Drug\|Genetic	1
Drug\|Other\|placebo	1
Drug\|Other\|Procedure	1
Genetic\|Other	1
placebo	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	369
NA	259
China	128
Korea, Republic of	55
United States\|Puerto Rico	53
France	44
Taiwan	44
Japan	41
Canada	34
Germany	31
Belgium	30
India	29
Spain	28
Egypt	27
United Kingdom	22
Netherlands	19
Thailand	19
Australia	17
Iran, Islamic Republic of	14
Russian Federation	14
Brazil	13
Italy	13
United States\|Canada	12
Hong Kong	10
New Zealand	10
Austria	9
Philippines	8
Switzerland	8
Turkey	7
Vietnam	7
Israel	6
Mexico	6
Sweden	6
Australia\|New Zealand	5
Belgium\|France	5
Denmark	5
Pakistan	5
Singapore	5
South Africa	5
Belgium\|Czech Republic\|Hungary	4
China\|Korea, Republic of	4
Norway	4
Poland	4
United States\|New Zealand	4
Belgium\|Germany	3
Colombia\|Costa Rica	3
Czech Republic	3
Indonesia	3
Moldova, Republic of	3
Puerto Rico	3
United States\|France\|Germany\|Spain	3
Bangladesh	2
Belgium\|Czechia	2
Belgium\|Germany\|United Kingdom	2
Belgium\|Netherlands	2
Bulgaria	2
China\|Hong Kong	2
Cuba	2
Czech Republic\|Malaysia\|Spain	2
Hong Kong\|Korea, Republic of	2
Kazakhstan	2
Philippines\|Thailand	2
Rwanda	2
Saudi Arabia	2
United States\|Australia\|Canada\|France\|Germany\|New Zealand\|Puerto Rico\|United Kingdom	2
United States\|Australia\|Canada\|Korea, Republic of\|New Zealand	2
United States\|Canada\|Hong Kong\|Italy\|Korea, Republic of\|New Zealand\|Taiwan\|United Kingdom	2
United States\|Canada\|Hong Kong\|New Zealand\|United Kingdom	2
United States\|France	2
United States\|France\|Puerto Rico	2
United States\|Germany	2
United States\|New Zealand\|Singapore\|Taiwan	2
Algeria\|Australia\|Austria\|Belgium\|Bulgaria\|Canada\|Denmark\|Finland\|France\|Germany\|Greece\|Ireland\|Israel\|Italy\|Mexico\|Netherlands\|Norway\|Poland\|Portugal\|Romania\|Russian Federation\|Saudi Arabia\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
Argentina	1
Argentina\|Brazil\|Germany\|Thailand	1
Argentina\|United States\|Australia\|Belgium\|Canada\|France\|Germany\|Hong Kong\|Hungary\|Italy\|Korea, Republic of\|Mexico\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Spain\|Taiwan\|Thailand\|United Kingdom\|Vietnam	1
Australia\|Argentina\|Canada\|Mexico\|New Zealand\|Thailand	1
Australia\|Belgium	1
Australia\|Belgium\|Canada\|Germany\|Norway\|Switzerland\|United Kingdom	1
Australia\|Belgium\|Spain	1
Australia\|Belgium\|Ukraine	1
Australia\|Brazil\|France\|Poland\|Russian Federation\|Spain\|Sweden\|United Kingdom	1
Australia\|Bulgaria\|China\|Hong Kong\|Korea, Republic of\|New Zealand\|Singapore\|Taiwan\|Thailand	1
Australia\|Canada\|Czech Republic\|France\|Germany\|Israel\|Poland\|Romania	1
Australia\|Canada\|Czechia\|Finland\|Italy\|Spain	1
Australia\|Canada\|France\|Germany\|Greece\|India\|Italy\|Poland\|Spain\|Taiwan\|Thailand\|United Kingdom	1
Australia\|Canada\|Israel\|New Zealand\|Spain\|United Kingdom	1
Australia\|Czech Republic\|Germany\|Italy\|Netherlands\|Switzerland\|United Kingdom	1
Australia\|France	1
Australia\|France\|Germany\|Italy\|Spain\|United Kingdom	1
Australia\|Germany\|Poland\|Romania\|Spain\|Taiwan	1
Australia\|Hong Kong\|Korea, Republic of\|New Zealand\|Singapore\|Taiwan\|Thailand	1
Australia\|Hong Kong\|Korea, Republic of\|New Zealand\|Thailand	1
Australia\|Hong Kong\|Korea, Republic of\|Taiwan\|United Kingdom	1
Australia\|Hong Kong\|New Zealand	1
Australia\|New Zealand\|United Kingdom	1
Australia\|Thailand	1
Austria\|Belgium\|Denmark\|Iceland	1
Austria\|Belgium\|France\|Germany\|Japan\|Portugal\|Romania\|Russian Federation\|Spain\|Switzerland\|United Kingdom	1
Austria\|Belgium\|France\|Germany\|Netherlands\|Spain	1
Austria\|Belgium\|France\|Germany\|Saudi Arabia\|Spain\|United Kingdom	1
Austria\|Belgium\|France\|Germany\|Spain\|United Kingdom	1
Austria\|Brazil\|France\|Greece\|Indonesia\|Italy\|Turkey\|United Arab Emirates	1
Austria\|France\|Germany\|United Kingdom	1
Austria\|Germany\|Hungary\|Poland\|Romania\|Spain	1
Belarus\|India\|Russian Federation\|Thailand	1
Belgium\|Bulgaria\|France\|Georgia\|Germany\|Malaysia\|Moldova, Republic of\|Romania\|Spain\|Taiwan	1
Belgium\|Canada	1
Belgium\|Canada\|Germany\|Poland\|Singapore\|Spain	1
Belgium\|Canada\|Sweden	1
Belgium\|Czech Republic	1
Belgium\|Czechia\|Germany	1
Belgium\|Denmark	1
Belgium\|France\|Germany\|Hungary\|Spain\|United Kingdom	1
Belgium\|France\|Germany\|Italy\|Poland\|Romania\|Spain	1
Belgium\|France\|Germany\|Italy\|Poland\|Spain\|United Kingdom	1
Belgium\|France\|Germany\|Netherlands\|Poland\|United Kingdom	1
Belgium\|France\|Germany\|United Kingdom	1
Belgium\|Germany\|Hungary\|Ireland\|Luxembourg\|Portugal\|Russian Federation\|United Kingdom	1
Belgium\|Germany\|Philippines\|United Kingdom	1
Belgium\|Germany\|Poland\|United Kingdom	1
Belgium\|Germany\|Thailand	1
Belgium\|Mauritius\|Moldova, Republic of	1
Belgium\|Moldova, Republic of	1
Brazil\|United States\|Australia\|Canada\|China\|France\|Germany\|Israel\|Korea, Republic of\|New Zealand\|Poland\|Puerto Rico\|Singapore\|Switzerland\|Taiwan\|Thailand\|United Kingdom	1
Bulgaria\|China\|Hong Kong\|Korea, Republic of\|New Zealand\|Poland\|Taiwan\|United Kingdom	1
Bulgaria\|Former Yugoslavia	1
Bulgaria\|Hong Kong\|Italy\|Netherlands\|New Zealand\|Taiwan\|Thailand\|United Kingdom	1
Bulgaria\|Israel\|Romania	1
Bulgaria\|Romania	1
Burkina Faso\|Ghana	1
CÃ´te D’Ivoire	1
Cambodia	1
Cameroon\|CÃ´te D’Ivoire\|Senegal	1
Canada\|China\|France\|Hong Kong\|Korea, Republic of\|New Zealand\|Spain\|Taiwan\|Thailand\|United Kingdom	1
Canada\|France\|Germany	1
Canada\|Germany	1
Canada\|Hong Kong\|Korea, Republic of\|Taiwan	1
Canada\|Korea, Republic of\|Taiwan	1
Canada\|Moldova, Republic of\|Ukraine	1
Canada\|Netherlands	1
Canada\|United Kingdom	1
Canada\|United States\|Argentina\|Australia\|Austria\|France\|Germany\|Ireland\|Israel\|Italy\|Korea, Republic of\|Netherlands\|New Zealand\|Poland\|Russian Federation\|Spain\|Taiwan\|United Kingdom	1
Canada\|United States\|Australia\|Austria\|Belgium\|France\|Germany\|New Zealand\|Poland\|Puerto Rico\|Russian Federation\|Spain\|United Kingdom	1
Chile	1
China\|Hong Kong\|Japan\|Korea, Republic of\|Philippines\|Singapore	1
China\|Korea, Republic of\|Russian Federation	1
China\|Korea, Republic of\|Singapore	1
China\|Korea, Republic of\|Taiwan	1
China\|Netherlands	1
China\|Netherlands\|Poland\|Romania\|Turkey	1
China\|United Kingdom	1
Colombia	1
Congo, The Democratic Republic of the	1
Czech Republic\|France\|Germany\|Italy\|Poland\|Spain\|Sweden\|United Kingdom	1
Czech Republic\|Korea, Republic of\|Mexico	1
Czechia\|Slovakia	1
Denmark\|Ethiopia\|Norway\|Sweden	1
Denmark\|United Kingdom\|United States	1
Estonia\|Latvia\|Lithuania	1
Estonia\|Russian Federation	1
Finland	1
Finland\|Sweden	1
France\|Denmark\|United States\|Australia\|Austria\|Belgium\|Canada\|Germany\|New Zealand\|Norway\|Poland\|Russian Federation\|Spain	1
France\|Georgia\|Moldova, Republic of	1
France\|Germany\|Greece\|Italy\|Spain	1
France\|Germany\|Italy\|Netherlands\|Poland\|Romania\|Spain	1
France\|Germany\|Netherlands	1
France\|Germany\|United States\|Belgium\|Brazil\|Canada\|Greece\|Italy\|Portugal\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
France\|Italy\|Spain\|United Kingdom	1
France\|Italy\|Switzerland	1
France\|Moldova, Republic of\|Romania	1
France\|Moldova, Republic of\|Romania\|Russian Federation	1
France\|Netherlands\|Poland	1
France\|New Zealand\|Poland	1
France\|Spain	1
France\|Sweden\|United Kingdom	1
France\|United States\|Belgium\|Brazil\|Canada\|Denmark\|Germany\|Hungary\|Netherlands\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Sweden\|United Kingdom	1
Georgia	1
Germany\|Greece\|Romania	1
Germany\|Hong Kong\|India\|Israel\|Italy\|China\|Czech Republic\|France\|United States\|Australia\|Canada\|Korea, Republic of\|New Zealand\|Poland\|Puerto Rico\|Singapore\|Spain\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
Germany\|Hong Kong\|Korea, Republic of\|New Zealand\|Singapore\|United Kingdom	1
Germany\|Israel\|Mexico\|United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|France\|Netherlands\|New Zealand\|Poland\|Portugal\|Puerto Rico\|Romania\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
Germany\|Netherlands	1
Germany\|Poland\|Spain	1
Germany\|Poland\|Sweden\|United Kingdom	1
Germany\|Russian Federation	1
Germany\|United Kingdom	1
Germany\|United States\|Argentina\|Belgium\|Chile\|Egypt\|Estonia\|France\|Greece\|Italy\|Kuwait\|Latvia\|Lebanon\|Lithuania\|Macedonia, The Former Yugoslav Republic of\|Mexico\|Oman\|Pakistan\|Peru\|Portugal\|Qatar\|Romania\|Serbia\|Slovakia\|Sweden\|Switzerland\|Syrian Arab Republic\|Taiwan\|Turkey\|United Arab Emirates\|Venezuela	1
Germany\|United States\|Australia\|Austria\|Canada\|France\|Italy\|Puerto Rico\|Spain\|United Kingdom	1
Germany\|United States\|Belgium\|Canada\|France\|Hong Kong\|Italy\|Puerto Rico\|United Kingdom	1
Greece\|Austria\|Bulgaria\|Germany\|Italy\|Russian Federation\|Spain\|Turkey	1
Guadeloupe	1
Hong Kong\|Korea, Republic of\|Malaysia\|New Zealand\|Singapore\|Taiwan	1
Hong Kong\|Korea, Republic of\|Singapore\|Taiwan\|Vietnam	1
Hong Kong\|New Zealand\|Singapore	1
Hong Kong\|Singapore\|Taiwan\|Thailand	1
Indonesia\|Malaysia\|Thailand\|Vietnam	1
Israel\|New Zealand\|Pakistan	1
Israel\|United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|France\|Germany\|India\|Korea, Republic of\|Malaysia\|Mexico\|Poland\|Puerto Rico\|Singapore\|Spain\|Sweden\|Taiwan\|Thailand\|United Kingdom	1
Korea, Republic of\|Moldova, Republic of\|New Zealand\|Thailand\|Ukraine	1
Korea, Republic of\|Russian Federation\|Taiwan	1
Korea, Republic of\|Taiwan	1
Korea, Republic of\|Taiwan\|Thailand	1
Korea, Republic of\|United Kingdom	1
Lao People’s Democratic Republic\|Thailand	1
Lebanon	1
Mauritius\|Moldova, Republic of\|New Zealand\|United Kingdom	1
Mauritius\|United Kingdom	1
Mexico\|Peru	1
Morocco	1
Myanmar	1
Nepal	1
Panama	1
Peru	1
Puerto Rico\|Spain\|Sweden\|Poland\|United States\|Australia\|Austria\|Belgium\|Brazil\|Canada\|France\|Germany\|Israel\|Netherlands\|Switzerland\|United Kingdom	1
Romania	1
Russian Federation\|Sweden	1
Russian Federation\|United States\|Argentina\|Australia\|Belgium\|Chile\|Finland\|France\|Greece\|Hong Kong\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|New Zealand\|Singapore\|Taiwan\|United Kingdom	1
Slovakia	1
Spain\|Australia\|Canada\|Czechia\|Finland\|Italy	1
Spain\|Sweden\|Switzerland\|Romania\|United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|Czech Republic\|Denmark\|France\|Germany\|Greece\|Hungary\|Israel\|Norway\|Poland\|Portugal\|Puerto Rico\|United Kingdom	1
Spain\|Switzerland\|United Kingdom	1
Spain\|United States\|Australia\|Belgium\|Brazil\|Canada\|Czech Republic\|France\|Germany\|Hong Kong\|India\|Israel\|Italy\|Korea, Republic of\|Netherlands\|Pakistan\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Slovakia\|Taiwan\|Thailand\|Ukraine\|United Kingdom	1
Taiwan\|United States\|Brazil\|Canada\|France\|Greece\|Hong Kong\|India\|Indonesia\|Philippines\|Poland\|Russian Federation\|Singapore\|South Africa\|Thailand\|Turkey\|United Kingdom	1
Thailand\|Australia\|Brazil\|China\|Hong Kong\|Korea, Republic of\|New Zealand\|Russian Federation\|Singapore\|Taiwan	1
Thailand\|Australia\|Hong Kong\|Korea, Republic of\|New Zealand	1
Turkey\|United States\|Austria\|Bulgaria\|Canada\|Czech Republic\|Germany\|Greece\|Hungary\|New Zealand\|Poland\|Romania\|Serbia\|Spain	1
Uganda	1
Ukraine	1
United Kingdom\|United States\|Australia\|Bulgaria\|Canada\|Czech Republic\|France\|Germany\|Greece\|Italy\|Netherlands\|New Zealand\|Poland\|Spain\|Turkey	1
United States\|Argentina	1
United States\|Argentina\|Australia\|Austria\|Brazil\|Canada\|Denmark\|France\|Germany\|Israel\|Italy\|Poland\|Russian Federation\|Spain\|Switzerland\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Canada\|Czech Republic\|France\|Germany\|Korea, Republic of\|Netherlands\|Portugal\|Romania\|Spain\|Switzerland\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Canada\|Denmark\|France\|Germany\|Greece\|Ireland\|Italy\|Korea, Republic of\|Mexico\|New Zealand\|Poland\|Spain\|Sweden\|Taiwan\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Canada\|France\|Germany\|Israel\|Italy\|Poland\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|France\|Germany\|Italy\|Puerto Rico\|Russian Federation\|Spain\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Canada\|France\|Germany\|Hong Kong\|Hungary\|India\|Italy\|Korea, Republic of\|Mexico\|Poland\|Romania\|Russian Federation\|Spain\|Taiwan\|Thailand\|Turkey\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Brazil\|Canada\|France\|India\|Italy\|Mexico\|Poland\|Russian Federation\|South Africa\|Turkey	1
United States\|Argentina\|Australia\|Brazil\|France\|Italy\|Korea, Republic of\|Spain\|Taiwan	1
United States\|Argentina\|Australia\|Canada\|Denmark\|France\|Germany\|Italy\|Mexico\|Puerto Rico\|Sweden	1
United States\|Argentina\|Australia\|Canada\|France\|Israel\|Italy\|Poland\|Puerto Rico\|Russian Federation\|Spain\|United Kingdom	1
United States\|Argentina\|Austria\|Belgium\|Brazil\|Bulgaria\|France\|Germany\|Netherlands\|Poland\|Portugal\|Puerto Rico\|Slovakia\|Spain\|Turkey	1
United States\|Argentina\|Belgium\|Brazil\|Canada\|Korea, Republic of\|Taiwan\|United Kingdom	1
United States\|Argentina\|Belgium\|Canada\|Germany\|Greece\|India\|Israel\|Korea, Republic of\|Poland\|Romania\|Russian Federation\|Taiwan\|United Kingdom	1
United States\|Argentina\|Canada\|Denmark\|France\|Germany\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Russian Federation\|Spain\|Sweden\|Switzerland\|Taiwan	1
United States\|Argentina\|Canada\|Puerto Rico	1
United States\|Argentina\|France\|Germany\|Hungary\|Spain	1
United States\|Argentina\|France\|Germany\|Ireland\|Italy\|Spain\|United Kingdom	1
United States\|Argentina\|France\|Germany\|Israel\|Italy\|Japan\|Korea, Republic of\|Poland\|Russian Federation\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Germany\|Mexico\|Puerto Rico\|Switzerland	1
United States\|Australia\|Austria\|Belgium\|Brazil\|France\|Germany\|Ireland\|Mexico\|Poland\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|France\|Germany\|Israel\|New Zealand\|Norway\|Poland\|Portugal\|Russian Federation\|United Kingdom	1
United States\|Australia\|Austria\|Brazil\|Canada\|France\|Germany\|Italy\|Mexico\|Poland\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|Czech Republic\|France\|Germany\|India\|Israel\|Italy\|Poland\|Puerto Rico\|Romania\|Spain\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|France\|Germany\|Italy	1
United States\|Australia\|Austria\|Canada\|France\|Germany\|Italy\|Puerto Rico\|Spain	1
United States\|Australia\|Belgium\|Brazil\|Canada\|Czech Republic\|Egypt\|France\|Germany\|Greece\|India\|Israel\|Italy\|Korea, Republic of\|Pakistan\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Slovakia\|Spain\|Taiwan\|Ukraine	1
United States\|Australia\|Belgium\|Brazil\|Canada\|France\|Germany\|Israel\|Netherlands\|Poland\|Puerto Rico\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Australia\|Belgium\|Bulgaria\|China\|Germany\|Israel\|Italy\|Poland\|Russian Federation\|Ukraine\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|Greece\|Italy\|New Zealand\|Portugal\|Spain\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|Germany\|India\|Italy\|Korea, Republic of\|Poland\|Puerto Rico\|Taiwan\|Thailand\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|France\|New Zealand\|Singapore\|South Africa\|Vietnam	1
United States\|Australia\|Belgium\|Canada\|Germany\|New Zealand\|Puerto Rico\|United Kingdom	1
United States\|Australia\|Belgium\|France\|Germany\|Hungary\|Italy\|Poland\|Puerto Rico\|Romania\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Belgium\|Germany\|Italy\|Malaysia\|Romania\|Russian Federation\|Taiwan\|Turkey\|Ukraine\|United Kingdom	1
United States\|Australia\|Belgium\|Germany\|Puerto Rico\|Spain\|Taiwan	1
United States\|Australia\|Brazil\|Canada\|China\|Germany\|Korea, Republic of\|New Zealand\|Russian Federation\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Australia\|Brazil\|Canada\|Greece\|Hong Kong\|India\|Indonesia\|Italy\|Korea, Republic of\|Malaysia\|Philippines\|Poland\|Russian Federation\|Singapore\|Taiwan\|Thailand\|Turkey	1
United States\|Australia\|Brazil\|China\|France\|Germany\|Hong Kong\|Korea, Republic of\|New Zealand\|Russian Federation\|Singapore\|Taiwan\|Thailand	1
United States\|Australia\|Brazil\|France\|Greece\|Italy\|Poland\|Puerto Rico\|Spain\|Taiwan\|United Kingdom	1
United States\|Australia\|Bulgaria\|Canada\|Czech Republic\|France\|Germany\|Greece\|Italy\|Netherlands\|New Zealand\|Poland\|Spain\|Turkey\|United Kingdom	1
United States\|Australia\|Bulgaria\|Canada\|France\|Hong Kong\|India\|Italy\|Japan\|Korea, Republic of\|New Zealand\|Poland\|Romania\|Russian Federation\|Singapore\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Canada\|China\|France\|Germany\|India\|Israel\|Korea, Republic of\|Latvia\|Malaysia\|New Zealand\|Poland\|Russian Federation\|Singapore\|Spain\|Taiwan\|Thailand\|Turkey\|United Kingdom\|Vietnam	1
United States\|Australia\|Canada\|China\|France\|Israel\|New Zealand\|Singapore\|Taiwan\|Thailand\|United Kingdom	1
United States\|Australia\|Canada\|China\|France\|Korea, Republic of\|Singapore\|Taiwan\|Thailand	1
United States\|Australia\|Canada\|Czechia\|Germany\|Israel\|Korea, Republic of\|Malaysia\|New Zealand\|Puerto Rico\|Romania\|Russian Federation\|Singapore\|Taiwan	1
United States\|Australia\|Canada\|Denmark\|Egypt\|France\|Germany\|Italy\|Mexico\|Puerto Rico\|Sweden	1
United States\|Australia\|Canada\|Denmark\|France\|Italy	1
United States\|Australia\|Canada\|France	1
United States\|Australia\|Canada\|France\|Germany\|Greece\|Hong Kong\|India\|Italy\|Korea, Republic of\|Netherlands\|Poland\|Portugal\|Romania\|Singapore\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|Greece\|Italy\|Pakistan\|Spain	1
United States\|Australia\|Canada\|France\|Germany\|Hong Kong\|Italy\|Korea, Republic of\|Netherlands\|Singapore\|Taiwan	1
United States\|Australia\|Canada\|France\|Germany\|Hong Kong\|New Zealand\|Poland\|Singapore\|Taiwan\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|New Zealand\|Puerto Rico\|Spain	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|New Zealand\|Puerto Rico\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|New Zealand\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|New Zealand\|Switzerland\|United Kingdom	1
United States\|Australia\|Canada\|France\|Hong Kong\|India\|Italy\|Japan\|Korea, Republic of\|New Zealand\|Poland\|Romania\|Russian Federation\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Canada\|France\|New Zealand\|Poland\|Slovakia	1
United States\|Australia\|Canada\|France\|Puerto Rico	1
United States\|Australia\|Canada\|Germany\|Mexico\|New Zealand\|Puerto Rico\|Romania\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
United States\|Australia\|Canada\|Germany\|Netherlands\|New Zealand\|Switzerland\|United Kingdom	1
United States\|Australia\|Canada\|New Zealand	1
United States\|Australia\|Canada\|New Zealand\|Puerto Rico	1
United States\|Australia\|Canada\|New Zealand\|United Kingdom	1
United States\|Australia\|China\|Hong Kong\|Korea, Republic of\|New Zealand\|United Kingdom	1
United States\|Australia\|France\|Germany\|Italy\|Japan\|New Zealand\|Puerto Rico\|Spain	1
United States\|Australia\|Germany\|New Zealand\|Poland	1
United States\|Australia\|Hong Kong\|New Zealand\|Philippines\|Singapore\|Taiwan\|Thailand	1
United States\|Australia\|New Zealand	1
United States\|Australia\|New Zealand\|Puerto Rico	1
United States\|Australia\|Puerto Rico	1
United States\|Australia\|Spain\|United Kingdom	1
United States\|Austria\|Belgium\|Brazil\|Canada\|Czechia\|France\|Germany\|Israel\|Italy\|Poland\|Russian Federation\|Spain\|Switzerland\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|Czech Republic\|France\|Germany\|Italy\|Poland\|Spain\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|France\|Germany\|Japan\|Korea, Republic of\|Portugal\|Romania\|Russian Federation\|Spain\|Switzerland\|Taiwan\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|France\|Germany\|Japan\|Portugal\|Puerto Rico\|Spain\|Switzerland\|United Kingdom	1
United States\|Austria\|Belgium\|Canada\|France\|Switzerland\|United Kingdom	1
United States\|Austria\|Belgium\|France\|Germany\|Netherlands\|Poland\|United Kingdom	1
United States\|Austria\|Brazil\|Canada\|France\|Germany\|Italy\|Mexico\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Austria\|Canada\|France\|Germany\|Netherlands\|Puerto Rico\|United Kingdom	1
United States\|Austria\|Canada\|France\|Germany\|Romania	1
United States\|Austria\|Canada\|France\|Germany\|Spain	1
United States\|Belgium	1
United States\|Belgium\|Brazil\|Canada\|China\|Czechia\|France\|Germany\|Hong Kong\|Italy\|Japan\|Korea, Republic of\|Malaysia\|Poland\|Russian Federation\|Spain\|Thailand\|Turkey\|United Kingdom	1
United States\|Belgium\|Brazil\|Canada\|Colombia\|France\|Germany\|Italy\|Korea, Republic of\|Russian Federation\|Spain\|Switzerland\|United Kingdom	1
United States\|Belgium\|Bulgaria\|Canada\|France\|Germany\|Greece\|Israel\|Italy\|Moldova, Republic of\|Mongolia\|New Zealand\|Pakistan\|Romania\|Spain\|Sweden\|Switzerland\|Taiwan\|Turkey\|United Kingdom	1
United States\|Belgium\|Bulgaria\|France\|Germany\|Puerto Rico	1
United States\|Belgium\|Canada\|China\|France\|Germany\|Hong Kong\|Italy\|Japan\|Korea, Republic of\|Malaysia\|Poland\|Russian Federation\|Spain\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
United States\|Belgium\|Canada\|China\|France\|Germany\|Italy\|Puerto Rico\|United Kingdom	1
United States\|Belgium\|Canada\|Czechia\|Denmark\|Germany\|Japan\|Netherlands\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Belgium\|Canada\|Finland	1
United States\|Belgium\|Canada\|France\|Germany\|Hungary\|Korea, Republic of\|Puerto Rico\|Spain	1
United States\|Belgium\|Canada\|France\|Germany\|Poland\|Russian Federation	1
United States\|Belgium\|Canada\|Germany\|Japan\|Puerto Rico\|Russian Federation\|Spain\|United Kingdom	1
United States\|Belgium\|Canada\|Germany\|United Kingdom	1
United States\|Belgium\|Canada\|Hong Kong\|India\|Korea, Republic of\|New Zealand\|Romania\|Russian Federation\|Taiwan	1
United States\|Belgium\|Germany\|Italy\|Taiwan	1
United States\|Belgium\|Germany\|Puerto Rico\|Spain	1
United States\|Belgium\|Netherlands\|Puerto Rico	1
United States\|Brazil\|France\|Germany\|Italy\|Spain\|Switzerland\|United Kingdom	1
United States\|Brazil\|France\|New Zealand\|Sweden	1
United States\|Brazil\|Mexico\|Puerto Rico\|South Africa	1
United States\|Brazil\|South Africa	1
United States\|Bulgaria\|Canada\|Czechia\|France\|Greece\|Hungary\|Ireland\|Israel\|Italy\|Poland\|Portugal\|Puerto Rico\|Romania\|Russian Federation\|Spain\|Taiwan\|United Kingdom\|Vietnam	1
United States\|Bulgaria\|Canada\|France\|Germany\|Poland\|Puerto Rico\|Russian Federation\|Spain\|United Kingdom	1
United States\|Bulgaria\|France\|Poland\|Romania\|Spain\|Turkey	1
United States\|Canada\|China\|France	1
United States\|Canada\|France\|Germany\|Greece\|Italy\|Poland\|Singapore\|Spain\|Taiwan\|Turkey	1
United States\|Canada\|France\|Germany\|Italy\|Puerto Rico\|Spain	1
United States\|Canada\|France\|Germany\|Italy\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Portugal\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Canada\|Germany	1
United States\|Canada\|Germany\|Greece\|Italy\|Korea, Republic of\|Poland\|Puerto Rico\|Spain\|Sweden	1
United States\|Canada\|Germany\|Netherlands\|Puerto Rico	1
United States\|Canada\|Germany\|Poland\|United Kingdom	1
United States\|Canada\|Hong Kong\|Indonesia\|Philippines\|Singapore\|Taiwan\|Thailand	1
United States\|Canada\|Hong Kong\|Italy\|Korea, Republic of\|Spain\|Taiwan\|United Kingdom	1
United States\|Canada\|Italy\|Korea, Republic of\|Netherlands\|New Zealand	1
United States\|Canada\|Italy\|Korea, Republic of\|New Zealand\|Romania	1
United States\|Canada\|Korea, Republic of\|Puerto Rico\|Taiwan	1
United States\|Canada\|New Zealand	1
United States\|Canada\|New Zealand\|Puerto Rico	1
United States\|Canada\|United Kingdom	1
United States\|China\|Korea, Republic of\|Singapore\|Taiwan	1
United States\|Czechia\|France\|Germany\|Hungary\|Poland\|Puerto Rico\|Spain\|United Kingdom	1
United States\|France\|Germany\|Italy\|Puerto Rico\|Spain\|United Kingdom	1
United States\|France\|Germany\|New Zealand	1
United States\|France\|Germany\|New Zealand\|Spain	1
United States\|France\|Germany\|Puerto Rico\|United Kingdom	1
United States\|France\|Greece\|Italy\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Germany\|Italy\|Russian Federation\|Sweden	1
United States\|Germany\|Netherlands\|Poland\|Puerto Rico\|Slovakia	1
United States\|Germany\|Spain\|United Kingdom	1
United States\|India\|Korea, Republic of\|Romania\|Taiwan	1
United States\|Japan\|Korea, Republic of\|Taiwan	1
United States\|Korea, Republic of\|Spain\|Thailand\|Turkey\|United Kingdom	1
United States\|New Zealand\|Spain	1
United States\|Russian Federation	1
United States\|United Kingdom	1
Zambia	1

Sites per Study

Site_count	Study_Count
1	947
2	110
3	68
4	62
5	36
6	32
7	33
8	33
9	19
10	24
11	28
12	18
13	9
14	15
15	20
16	16
17	10
18	17
19	16
20	14
21	16
22	9
23	10
24	13
25	15
26	7
27	6
28	11
29	3
30	3
31	5
32	10
33	3
34	4
35	5
36	2
37	5
38	8
39	6
40	4
41	4
42	6
43	6
44	3
45	4
46	1
48	7
49	4
50	1
51	4
52	2
53	4
54	1
55	3
56	1
60	1
61	2
62	2
63	3
64	1
66	3
67	4
68	2
71	3
72	1
73	3
74	1
75	1
76	2
77	1
78	1
79	1
80	2
81	1
82	1
86	2
87	3
88	1
91	1
93	3
97	1
98	1
100	3
101	1
102	1
104	2
105	1
106	1
107	1
109	1
112	1
113	1
114	1
116	3
119	1
121	1
123	1
124	1
132	1
142	1
144	1
147	1
159	2
165	1
171	1
184	1
187	1
191	1
210	1
227	1

Phase

Phase	Study_Count
Phase 3	445
Phase 2	425
Phase 4	373
N/A	229
Phase 1	222
Phase 1/Phase 2	62
Phase 2/Phase 3	44
Early Phase 1	5

Number of Arms

Number_of_Arms	Count_of_Studies
1	401
2	648
3	248
4	145
5	48
6	54
7	22
8	17
9	7
10	10
11	4
12	6
13	1
14	3
18	2
20	1
22	3
27	1
NA	184

Number of Updates

Count of Versions	Count of Studies
1	147
2	197
3	143
4	146
5	133
6	124
7	91
8	89
9	77
10	71
11	46
12	37
13	42
14	31
15	27
16	14
17	15
18	25
19	13
20	16
21	19
22	15
23	8
24	11
25	8
26	19
27	13
28	12
29	9
30	5
31	9
32	8
33	6
34	7
35	11
36	5
37	9
38	4
39	3
40	6
41	2
42	9
43	3
44	5
45	3
46	4
47	3
48	5
49	4
50	2
51	3
52	2
53	3
54	2
55	2
57	2
58	2
59	3
60	1
61	2
62	3
63	1
64	4
65	1
66	3
68	1
69	1
71	1
72	1
73	1
74	2
75	1
76	3
77	1
78	1
80	2
81	1
82	1
83	1
84	1
85	7
87	2
88	1
89	2
90	2
91	4
92	2
93	1
94	1
97	1
99	1
101	1
103	3
110	1
117	1
121	1
125	1
134	2
150	2
161	1
173	1
254	1
589	1
904	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	23913	1658	14.422799
Contacts/Locations	8537	1443	5.916147
Recruitment Status	3178	1478	2.150203
Study Design	2651	1339	1.979836
Outcome Measures	2253	1013	2.224087
Arms	1892	961	1.968783
Interventions	1892	961	1.968783
None (earliest Version on record)	1805	1805	1.000000
Study Description	1778	825	2.155152
Study Identification	1632	855	1.908772
Eligibility	1628	858	1.897436
Sponsor/Collaborators	1503	834	1.802158
More Information	1199	417	2.875300
Oversight	881	682	1.291789
References	797	517	1.541586
Conditions	642	408	1.573529
Results	562	562	1.000000
IPDSharing	352	279	1.261649
Baseline Characteristics	321	239	1.343096
Reported Adverse Events	279	214	1.303738
Participant Flow	239	199	1.201005
Results Submission Events	98	98	1.000000
Documents	82	77	1.064935
2020Recruitment Status	1	1	1.000000
Quality Control Review has not concludedReturned: January 31	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	22.0	2.000	4.00000	6.00000	2.0000	10.0000	6.0000	5.000
1st Qu.	25.0	51.500	21.00000	24.00000	36.0000	71.0000	103.7500	54.750
Median	26.0	138.000	34.00000	38.50000	72.5000	121.0000	218.0000	131.500
Mean	35.4	1132.634	44.55856	56.98333	131.9143	273.3953	379.4908	1418.027
3rd Qu.	52.0	300.000	58.00000	64.25000	160.0000	345.0000	470.5000	303.750
Max.	52.0	50000.000	240.00000	548.00000	2000.0000	1400.0000	5000.0000	221855.000

Trial Group Type

group_type	Group_Count
Experimental	3084
Active Comparator	759
Placebo Comparator	262
NA	184
Other	147
No Intervention	101
Sham Comparator	5

Intervention Model

intervention_model	Study_Count
Parallel Assignment	1170
Single Group Assignment	520
Crossover Assignment	45
NA	34
Sequential Assignment	22
Factorial Assignment	14

Primary Purpose

primary_purpose	Study_Count
Treatment	1326
Prevention	295
Diagnostic	36
NA	32
Basic Science	31
Other	30
Health Services Research	25
Screening	19
Supportive Care	10
Device Feasibility	1

Observational Studies

Studies by Country

Country	Study_Count
United States	92
NA	72
China	45
France	23
Taiwan	16
Korea, Republic of	15
Spain	13
Germany	12
Australia	11
Japan	11
Netherlands	10
Canada	9
Egypt	9
Brazil	8
Hong Kong	7
India	7
United Kingdom	7
Denmark	6
Italy	5
United States\|Puerto Rico	5
Austria	4
Mexico	4
Russian Federation	4
Switzerland	4
United States\|Canada	4
Zambia	4
Israel	3
Turkey	3
Belgium	2
Bulgaria	2
Greece	2
Panama	2
Poland	2
Senegal	2
Singapore	2
Thailand	2
Australia\|France\|Hong Kong\|Italy\|Korea, Republic of\|New Zealand\|Russian Federation\|Singapore\|Taiwan\|Thailand	1
Austria\|Bahrain\|Bangladesh\|Bosnia and Herzegovina\|Bulgaria\|China\|Egypt\|France\|Germany\|Hong Kong\|India\|Indonesia\|Ireland\|Jordan\|Korea, Republic of\|Lebanon\|Macedonia, The Former Yugoslav Republic of\|Morocco\|New Zealand\|Pakistan\|Poland\|Portugal\|Romania\|Saudi Arabia\|Thailand\|United Arab Emirates\|United Kingdom	1
Austria\|Belgium\|France\|Greece\|Israel\|Italy\|Poland\|Portugal\|Switzerland	1
Austria\|Brazil\|Canada\|Croatia\|France\|Hungary\|Macedonia, The Former Yugoslav Republic of\|Mexico\|Morocco\|Poland\|Romania\|Serbia\|Slovenia\|Sweden	1
Austria\|Bulgaria\|China\|France\|Germany\|Greece\|Italy\|Korea, Republic of\|New Zealand\|Poland\|Portugal\|Romania\|Taiwan\|Thailand\|United Kingdom	1
Belgium\|Egypt\|Estonia\|France\|Germany\|Greece\|Hungary\|Ireland\|Italy\|Kuwait\|Lebanon\|Macedonia, The Former Yugoslav Republic of\|Morocco\|Oman\|Pakistan\|Portugal\|Qatar\|Romania\|Saudi Arabia\|Serbia\|Sweden\|Switzerland\|Syrian Arab Republic\|Taiwan\|Turkey\|United Arab Emirates\|United Kingdom	1
Belgium\|France\|Germany\|Netherlands\|Switzerland\|United Kingdom	1
Belgium\|Georgia\|Nigeria	1
Belgium\|Ireland\|Italy\|United Kingdom	1
Cambodia	1
Cambodia\|Georgia	1
China\|Japan	1
China\|Korea, Republic of\|Malaysia\|Singapore	1
China\|United States\|Argentina\|Brazil\|Canada\|Colombia\|Czechia\|France\|Germany\|Greece\|India\|Italy\|Korea, Republic of\|Mexico\|Philippines\|Poland\|Portugal\|Romania\|Russian Federation\|Singapore\|Spain\|Taiwan\|Thailand\|Turkey	1
Colombia	1
Czech Republic	1
Ethiopia	1
France\|Italy	1
Gambia\|Senegal	1
Georgia	1
Hungary	1
Iceland	1
Kenya	1
Korea, Republic of\|Russian Federation	1
Kuwait\|Lebanon\|Albania\|Algeria\|Bahrain\|Belgium\|Bosnia and Herzegovina\|Brazil\|Egypt\|Greece\|Hungary\|India\|Iran, Islamic Republic of\|Italy\|Korea, Republic of\|Macedonia, The Former Yugoslav Republic of\|Morocco\|Pakistan\|Poland\|Portugal\|Qatar\|Romania\|Serbia\|Slovakia\|United Arab Emirates	1
Moldova, Republic of	1
Myanmar	1
Netherlands\|United Kingdom	1
Norway	1
Puerto Rico	1
Romania\|United States\|Argentina\|Australia\|Austria\|Belgium\|Canada\|Finland\|France\|Germany\|Greece\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|New Zealand\|Poland\|Puerto Rico\|Spain	1
Romania\|United States\|Argentina\|Brazil\|China\|France\|Greece\|India\|Italy\|Peru\|Philippines\|Poland\|Russian Federation\|Singapore\|Spain\|Taiwan\|Thailand\|United Kingdom	1
Serbia	1
Slovenia	1
South Africa	1
Sweden	1
Uganda	1
Ukraine	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Denmark\|France\|Germany\|Ireland\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Puerto Rico\|Spain\|Sweden\|Taiwan\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Czechia\|Estonia\|France\|Germany\|Italy\|Netherlands\|New Zealand\|Poland\|Puerto Rico\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|Czechia\|Estonia\|France\|Germany\|Italy\|Netherlands\|New Zealand\|Poland\|Puerto Rico\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Bulgaria\|Canada\|Germany\|Hungary\|Italy\|New Zealand\|Romania\|Turkey	1
United States\|Canada\|Germany\|Puerto Rico	1
United States\|Egypt	1
Uzbekistan	1
Vietnam	1

Sites per Study

Site_count	Study_Count
1	332
2	24
3	12
4	13
5	4
6	6
7	5
8	4
9	6
10	3
11	5
12	2
14	1
16	1
17	2
18	2
19	2
21	2
22	1
25	1
26	2
27	3
28	1
30	1
33	1
34	1
37	2
39	1
43	1
45	2
46	1
50	1
53	1
57	1
58	1
59	1
61	1
66	1
70	1
72	1
74	1
75	1
84	1
86	1
88	1
90	1
101	1
104	1
106	1
125	1
156	1
161	1
170	1
249	1
261	1
266	1
272	1
290	1
323	1
325	1
388	1
402	1

Number of Updates

Count of Versions	Count of Studies
1	54
2	78
3	76
4	46
5	29
6	16
7	22
8	7
9	13
10	10
11	4
12	14
13	5
14	6
15	7
16	6
17	1
19	1
20	5
21	1
22	1
23	3
24	4
25	2
26	1
27	1
28	2
29	1
30	2
31	1
33	3
34	2
36	1
37	1
38	2
39	3
40	1
42	2
43	1
44	2
45	1
49	1
53	2
56	1
58	2
60	3
63	1
64	1
66	1
67	2
69	1
70	2
73	1
74	1
78	1
81	1
83	1
88	1
89	1
90	1
91	1
103	1
108	1
115	1
119	1
126	1
127	1
128	1
139	1
211	1
440	1
461	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	6586	421	15.643705
Contacts/Locations	1642	319	5.147335
Study Description	705	178	3.960674
Study Design	698	321	2.174455
Recruitment Status	603	327	1.844037
None (earliest Version on record)	475	475	1.000000
Eligibility	383	204	1.877451
Sponsor/Collaborators	283	172	1.645349
Study Identification	244	163	1.496932
Outcome Measures	233	170	1.370588
Groups	184	139	1.323741
Interventions	184	139	1.323741
Oversight	160	116	1.379310
References	134	75	1.786667
More Information	130	38	3.421053
Conditions	102	74	1.378378
Results	75	75	1.000000
IPDSharing	47	47	1.000000
Baseline Characteristics	29	20	1.450000
Documents	19	19	1.000000
Reported Adverse Events	15	12	1.250000
Results Submission Events	14	14	1.000000
Participant Flow	11	9	1.222222

Enrollment Metrics

Measure	Observational
Min	1.0000e+00
1st Qu	8.0250e+01
Median	2.9550e+02
Mean	2.1836e+05
3rd Qu	8.6950e+02
Max	1.0000e+08

Observation Model

observational_model	Study_Count
Cohort	301
Case-Only	51
NA	48
Other	24
Case-Control	21
Case Control	18
Ecologic or Community	8
Family-Based	2
Case-Crossover	1
Defined Population, Natural History	1

Time Perspective

time_perspective	Study_Count
Prospective	324
Retrospective	69
Cross-Sectional	34
NA	25
Other	22
Longitudinal, Prospective	1

Registries

Studies by Country

Country	Study_Count
China	8
NA	4
Spain	4
Korea, Republic of	3
United States	3
Egypt	2
France	2
Japan	2
Argentina	1
Argentina\|Austria\|Belarus\|Belgium\|Bosnia and Herzegovina\|Croatia\|Czechia\|Denmark\|Estonia\|Finland\|France\|Georgia\|Germany\|Greece\|Hungary\|Iceland\|Ireland\|Israel\|Italy\|Latvia\|Lithuania\|Luxembourg\|Netherlands\|Norway\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|Slovakia\|Slovenia\|Spain\|Sweden\|Switzerland\|Ukraine\|United Kingdom	1
Austria	1
Austria\|Belgium\|Brazil\|Georgia\|Germany\|Greece\|Italy\|Moldova, Republic of\|Pakistan\|Romania\|Spain\|Vietnam	1
Cameroon	1
Chile	1
Germany	1
Italy	1
Switzerland	1
Taiwan	1
United States\|Australia\|Belgium\|Germany\|Italy\|New Zealand\|Russian Federation\|United Kingdom	1
United States\|Australia\|Canada\|France\|Germany\|Italy\|New Zealand\|Puerto Rico\|Spain\|United Kingdom	1
United States\|Canada	1
United States\|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	29
2	1
3	1
13	1
15	1
18	2
27	1
30	1
45	1
48	2
110	1
138	1

Number of Updates

Count of Versions	Count of Studies
1	10
2	10
3	5
4	2
5	4
6	2
7	2
10	2
14	1
22	1
25	1
26	1
35	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	199	32	6.218750
Contacts/Locations	85	25	3.400000
None (earliest Version on record)	42	42	1.000000
Study Design	31	19	1.631579
Recruitment Status	29	20	1.450000
Sponsor/Collaborators	19	8	2.375000
Outcome Measures	16	13	1.230769
Study Description	16	12	1.333333
Eligibility	13	7	1.857143
Oversight	9	8	1.125000
Study Identification	9	6	1.500000
References	7	4	1.750000
Groups	5	5	1.000000
Interventions	5	5	1.000000
Conditions	3	3	1.000000
Documents	3	3	1.000000
IPDSharing	3	3	1.000000
Results	3	3	1.000000

Enrollment Metrics

Measure	Registries
Min	8.000
1st Qu	281.250
Median	500.000
Mean	6212.548
3rd Qu	1000.000
Max	200000.000

Registry Model

observational_model	Study_Count
Cohort	32
Case-Control	4
Case-Only	2
Other	2
Case-Crossover	1
NA	1

Time Perspective

time_perspective	Study_Count
Prospective	32
Cross-Sectional	5
Other	3
NA	2

Follow-up

target_duration	Study_Count
5 Years	8
1 Day	4
10 Years	4
1 Year	3
12 Months	3
24 Weeks	3
3 Years	2
48 Weeks	2
10 Months	1
144 Weeks	1
2 Weeks	1
2 Years	1
20 Years	1
3 Months	1
30 Years	1
36 Months	1
4 Years	1
6 Months	1
62 Months	1
64 Weeks	1
8 Months	1

intervention_type	Study_Count
Drug	979
Drug\|placebo	263
Biological	256
Behavioral	54
Other	53
Biological\|Drug	42
Biological\|Drug\|placebo	23
Device	18
Procedure	15
Biological\|placebo	13
Dietary Supplement	12
Drug\|Other	10
Diagnostic Test	8
Device\|Drug	7
Behavioral\|Other	6
Biological\|Other	5
Biological\|Procedure	4
Dietary Supplement\|placebo	4
Behavioral\|Biological	3
Behavioral\|Drug	3
Device\|Other	3
Dietary Supplement\|Drug	3
Other\|Procedure	3
Biological\|Drug\|Other	2
Drug\|Procedure	2
Genetic	2
Behavioral\|Diagnostic Test	1
Behavioral\|placebo	1
Biological\|Drug\|Procedure	1
Biological\|Other\|placebo	1
Diagnostic Test\|Drug	1
Dietary Supplement\|Drug\|Procedure	1
Dietary Supplement\|Other	1
Drug\|Genetic	1
Drug\|Other\|placebo	1
Drug\|Other\|Procedure	1
Genetic\|Other	1
placebo	1

Site_count	Study_Count
1	947
2	110
3	68
4	62
5	36
6	32
7	33
8	33
9	19
10	24
11	28
12	18
13	9
14	15
15	20
16	16
17	10
18	17
19	16
20	14
21	16
22	9
23	10
24	13
25	15
26	7
27	6
28	11
29	3
30	3
31	5
32	10
33	3
34	4
35	5
36	2
37	5
38	8
39	6
40	4
41	4
42	6
43	6
44	3
45	4
46	1
48	7
49	4
50	1
51	4
52	2
53	4
54	1
55	3
56	1
60	1
61	2
62	2
63	3
64	1
66	3
67	4
68	2
71	3
72	1
73	3
74	1
75	1
76	2
77	1
78	1
79	1
80	2
81	1
82	1
86	2
87	3
88	1
91	1
93	3
97	1
98	1
100	3
101	1
102	1
104	2
105	1
106	1
107	1
109	1
112	1
113	1
114	1
116	3
119	1
121	1
123	1
124	1
132	1
142	1
144	1
147	1
159	2
165	1
171	1
184	1
187	1
191	1
210	1
227	1

Number_of_Arms	Count_of_Studies
1	401
2	648
3	248
4	145
5	48
6	54
7	22
8	17
9	7
10	10
11	4
12	6
13	1
14	3
18	2
20	1
22	3
27	1
NA	184

Count of Versions	Count of Studies
1	147
2	197
3	143
4	146
5	133
6	124
7	91
8	89
9	77
10	71
11	46
12	37
13	42
14	31
15	27
16	14
17	15
18	25
19	13
20	16
21	19
22	15
23	8
24	11
25	8
26	19
27	13
28	12
29	9
30	5
31	9
32	8
33	6
34	7
35	11
36	5
37	9
38	4
39	3
40	6
41	2
42	9
43	3
44	5
45	3
46	4
47	3
48	5
49	4
50	2
51	3
52	2
53	3
54	2
55	2
57	2
58	2
59	3
60	1
61	2
62	3
63	1
64	4
65	1
66	3
68	1
69	1
71	1
72	1
73	1
74	2
75	1
76	3
77	1
78	1
80	2
81	1
82	1
83	1
84	1
85	7
87	2
88	1
89	2
90	2
91	4
92	2
93	1
94	1
97	1
99	1
101	1
103	3
110	1
117	1
121	1
125	1
134	2
150	2
161	1
173	1
254	1
589	1
904	1

Site_count	Study_Count
1	332
2	24
3	12
4	13
5	4
6	6
7	5
8	4
9	6
10	3
11	5
12	2
14	1
16	1
17	2
18	2
19	2
21	2
22	1
25	1
26	2
27	3
28	1
30	1
33	1
34	1
37	2
39	1
43	1
45	2
46	1
50	1
53	1
57	1
58	1
59	1
61	1
66	1
70	1
72	1
74	1
75	1
84	1
86	1
88	1
90	1
101	1
104	1
106	1
125	1
156	1
161	1
170	1
249	1
261	1
266	1
272	1
290	1
323	1
325	1
388	1
402	1

Count of Versions	Count of Studies
1	54
2	78
3	76
4	46
5	29
6	16
7	22
8	7
9	13
10	10
11	4
12	14
13	5
14	6
15	7
16	6
17	1
19	1
20	5
21	1
22	1
23	3
24	4
25	2
26	1
27	1
28	2
29	1
30	2
31	1
33	3
34	2
36	1
37	1
38	2
39	3
40	1
42	2
43	1
44	2
45	1
49	1
53	2
56	1
58	2
60	3
63	1
64	1
66	1
67	2
69	1
70	2
73	1
74	1
78	1
81	1
83	1
88	1
89	1
90	1
91	1
103	1
108	1
115	1
119	1
126	1
127	1
128	1
139	1
211	1
440	1
461	1

Site_count	Study_Count
1	947
2	110
3	68
4	62
5	36
6	32
7	33
8	33
9	19
10	24
11	28
12	18
13	9
14	15
15	20
16	16
17	10
18	17
19	16
20	14
21	16
22	9
23	10
24	13
25	15
26	7
27	6
28	11
29	3
30	3
31	5
32	10
33	3
34	4
35	5
36	2
37	5
38	8
39	6
40	4
41	4
42	6
43	6
44	3
45	4
46	1
48	7
49	4
50	1
51	4
52	2
53	4
54	1
55	3
56	1
60	1
61	2
62	2
63	3
64	1
66	3
67	4
68	2
71	3
72	1
73	3
74	1
75	1
76	2
77	1
78	1
79	1
80	2
81	1
82	1
86	2
87	3
88	1
91	1
93	3
97	1
98	1
100	3
101	1
102	1
104	2
105	1
106	1
107	1
109	1
112	1
113	1
114	1
116	3
119	1
121	1
123	1
124	1
132	1
142	1
144	1
147	1
159	2
165	1
171	1
184	1
187	1
191	1
210	1
227	1

Number_of_Arms	Count_of_Studies
1	401
2	648
3	248
4	145
5	48
6	54
7	22
8	17
9	7
10	10
11	4
12	6
13	1
14	3
18	2
20	1
22	3
27	1
NA	184

Count of Versions	Count of Studies
1	147
2	197
3	143
4	146
5	133
6	124
7	91
8	89
9	77
10	71
11	46
12	37
13	42
14	31
15	27
16	14
17	15
18	25
19	13
20	16
21	19
22	15
23	8
24	11
25	8
26	19
27	13
28	12
29	9
30	5
31	9
32	8
33	6
34	7
35	11
36	5
37	9
38	4
39	3
40	6
41	2
42	9
43	3
44	5
45	3
46	4
47	3
48	5
49	4
50	2
51	3
52	2
53	3
54	2
55	2
57	2
58	2
59	3
60	1
61	2
62	3
63	1
64	4
65	1
66	3
68	1
69	1
71	1
72	1
73	1
74	2
75	1
76	3
77	1
78	1
80	2
81	1
82	1
83	1
84	1
85	7
87	2
88	1
89	2
90	2
91	4
92	2
93	1
94	1
97	1
99	1
101	1
103	3
110	1
117	1
121	1
125	1
134	2
150	2
161	1
173	1
254	1
589	1
904	1

Site_count	Study_Count
1	332
2	24
3	12
4	13
5	4
6	6
7	5
8	4
9	6
10	3
11	5
12	2
14	1
16	1
17	2
18	2
19	2
21	2
22	1
25	1
26	2
27	3
28	1
30	1
33	1
34	1
37	2
39	1
43	1
45	2
46	1
50	1
53	1
57	1
58	1
59	1
61	1
66	1
70	1
72	1
74	1
75	1
84	1
86	1
88	1
90	1
101	1
104	1
106	1
125	1
156	1
161	1
170	1
249	1
261	1
266	1
272	1
290	1
323	1
325	1
388	1
402	1

Count of Versions	Count of Studies
1	54
2	78
3	76
4	46
5	29
6	16
7	22
8	7
9	13
10	10
11	4
12	14
13	5
14	6
15	7
16	6
17	1
19	1
20	5
21	1
22	1
23	3
24	4
25	2
26	1
27	1
28	2
29	1
30	2
31	1
33	3
34	2
36	1
37	1
38	2
39	3
40	1
42	2
43	1
44	2
45	1
49	1
53	2
56	1
58	2
60	3
63	1
64	1
66	1
67	2
69	1
70	2
73	1
74	1
78	1
81	1
83	1
88	1
89	1
90	1
91	1
103	1
108	1
115	1
119	1
126	1
127	1
128	1
139	1
211	1
440	1
461	1

hepatitis

Study Counts

Studies over Time

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Number of Updates

Update History Change Type

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Number of Updates

Update History Change Type

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Site_count	Study_Count
1	947
2	110
3	68
4	62
5	36
6	32
7	33
8	33
9	19
10	24
11	28
12	18
13	9
14	15
15	20
16	16
17	10
18	17
19	16
20	14
21	16
22	9
23	10
24	13
25	15
26	7
27	6
28	11
29	3
30	3
31	5
32	10
33	3
34	4
35	5
36	2
37	5
38	8
39	6
40	4
41	4
42	6
43	6
44	3
45	4
46	1
48	7
49	4
50	1
51	4
52	2
53	4
54	1
55	3
56	1
60	1
61	2
62	2
63	3
64	1
66	3
67	4
68	2
71	3
72	1
73	3
74	1
75	1
76	2
77	1
78	1
79	1
80	2
81	1
82	1
86	2
87	3
88	1
91	1
93	3
97	1
98	1
100	3
101	1
102	1
104	2
105	1
106	1
107	1
109	1
112	1
113	1
114	1
116	3
119	1
121	1
123	1
124	1
132	1
142	1
144	1
147	1
159	2
165	1
171	1
184	1
187	1
191	1
210	1
227	1

Number_of_Arms	Count_of_Studies
1	401
2	648
3	248
4	145
5	48
6	54
7	22
8	17
9	7
10	10
11	4
12	6
13	1
14	3
18	2
20	1
22	3
27	1
NA	184

Count of Versions	Count of Studies
1	147
2	197
3	143
4	146
5	133
6	124
7	91
8	89
9	77
10	71
11	46
12	37
13	42
14	31
15	27
16	14
17	15
18	25
19	13
20	16
21	19
22	15
23	8
24	11
25	8
26	19
27	13
28	12
29	9
30	5
31	9
32	8
33	6
34	7
35	11
36	5
37	9
38	4
39	3
40	6
41	2
42	9
43	3
44	5
45	3
46	4
47	3
48	5
49	4
50	2
51	3
52	2
53	3
54	2
55	2
57	2
58	2
59	3
60	1
61	2
62	3
63	1
64	4
65	1
66	3
68	1
69	1
71	1
72	1
73	1
74	2
75	1
76	3
77	1
78	1
80	2
81	1
82	1
83	1
84	1
85	7
87	2
88	1
89	2
90	2
91	4
92	2
93	1
94	1
97	1
99	1
101	1
103	3
110	1
117	1
121	1
125	1
134	2
150	2
161	1
173	1
254	1
589	1
904	1

Site_count	Study_Count
1	332
2	24
3	12
4	13
5	4
6	6
7	5
8	4
9	6
10	3
11	5
12	2
14	1
16	1
17	2
18	2
19	2
21	2
22	1
25	1
26	2
27	3
28	1
30	1
33	1
34	1
37	2
39	1
43	1
45	2
46	1
50	1
53	1
57	1
58	1
59	1
61	1
66	1
70	1
72	1
74	1
75	1
84	1
86	1
88	1
90	1
101	1
104	1
106	1
125	1
156	1
161	1
170	1
249	1
261	1
266	1
272	1
290	1
323	1
325	1
388	1
402	1

Count of Versions	Count of Studies
1	54
2	78
3	76
4	46
5	29
6	16
7	22
8	7
9	13
10	10
11	4
12	14
13	5
14	6
15	7
16	6
17	1
19	1
20	5
21	1
22	1
23	3
24	4
25	2
26	1
27	1
28	2
29	1
30	2
31	1
33	3
34	2
36	1
37	1
38	2
39	3
40	1
42	2
43	1
44	2
45	1
49	1
53	2
56	1
58	2
60	3
63	1
64	1
66	1
67	2
69	1
70	2
73	1
74	1
78	1
81	1
83	1
88	1
89	1
90	1
91	1
103	1
108	1
115	1
119	1
126	1
127	1
128	1
139	1
211	1
440	1
461	1